Description

6-Bromo-5-Chloroquinazolin-2-Amine is a high-purity, multi-halogenated quinazoline derivative, a crucial building block in modern organic synthesis. Its value lies in its versatile reactivity, serving as a key intermediate for constructing complex heterocyclic scaffolds with potential biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinazoline core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and cellular pathways.
• Material Science Research: Investigated as a building block for organic electronic materials and advanced polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules in multi-step syntheses.

Basic Information

Product Name	6-Bromo-5-Chloroquinazolin-2-Amine
CAS No.	1644663-97-7
Molecular Formula	C8H5BrClN3
Molecular Weight	258.50 g/mol
Synonyms	2-Amino-6-bromo-5-chloroquinazoline; 5-Chloro-6-bromoquinazolin-2-amine; 6-Bromo-5-chloro-2-quinazolinamine; 6-Bromo-5-chloroquinazolin-2-ylamine; Quinazoline, 2-amino-6-bromo-5-chloro-; 1644663-97-7
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Chloroquinazolin-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.