Description

(S)-2-Methyl-1,2,3,4-tetrahydroquinolin-1-ium chloride is a chiral, non-racemic organic salt of significant interest in advanced synthetic chemistry. This compound matters as a key chiral building block or intermediate for the development of novel pharmaceuticals and agrochemicals, where stereochemistry is critical for biological activity. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric synthesis, and the production of high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Catalysis: Used as a precursor or ligand component in the development of chiral catalysts for enantioselective synthesis.
• Agrochemical Research: Employed in the synthesis of novel, stereochemically-defined pesticides and herbicides.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for creating compound libraries for biological screening.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex, high-value specialty chemicals where the tetrahydroquinoline scaffold is required.

Basic Information

Product Name	(S)-2-Methyl-1,2,3,4-tetrahydroquinolin-1-ium chloride
CAS No.	1644660-41-2
Molecular Formula	C10H14ClN
Molecular Weight	183.68 g/mol
Synonyms	(S)-2-Methyl-1,2,3,4-tetrahydroquinolinium chloride; (S)-1,2,3,4-Tetrahydro-2-methylquinolin-1-ium chloride; (S)-2-Methyl-1,2,3,4-tetrahydroquinoline hydrochloride; (S)-N-Methyl-1,2,3,4-tetrahydroquinolin-2-ium chloride; (S)-2-Methyl-1,2,3,4-tetrahydroquinolin-1-ylium chloride; (S)-THQ-Me Cl; (S)-2-Me-THQ HCl
EINECS	Contact for details

Quality Control

Our (S)-2-Methyl-1,2,3,4-tetrahydroquinolin-1-ium chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC, Chiral SFC), to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC/SFC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.