Description

Di-tert-Butyl 1-(Trifluoromethyl)Hydrazine-1,2-Dicarboxylate is a specialized, high-value building block used in advanced organic synthesis. This compound is critical for the efficient introduction of the trifluoromethylhydrazine moiety, a key functional group that can impart desirable properties to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique structure enables the exploration of new chemical space and the optimization of compound properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating specialty polymers and advanced materials with tailored surface properties or specific reactivity.
• Fluorine Chemistry: An essential reagent for medicinal and synthetic chemists exploring the effects of fluorine substitution to modulate lipophilicity, metabolic stability, and binding affinity in lead compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex, high-value molecules under cGMP or research-grade conditions.

Basic Information

Product Name	Di-tert-Butyl 1-(Trifluoromethyl)Hydrazine-1,2-Dicarboxylate
CAS No.	1644529-01-0
Molecular Formula	C11H19F3N2O4
Molecular Weight	300.27 g/mol
Synonyms	1,2-Bis(tert-butoxycarbonyl)-1-(trifluoromethyl)hydrazine; Di-tert-butyl (trifluoromethyl)hydrazine-1,2-dicarboxylate; (Trifluoromethyl)hydrazine-1,2-dicarboxylic acid bis(1,1-dimethylethyl) ester; BOC-Trifluoromethylhydrazine; 1-(Trifluoromethyl)hydrazine-1,2-dicarboxylic acid di-tert-butyl ester; t-Butyl 1-(trifluoromethyl)hydrazine-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl 1-(Trifluoromethyl)Hydrazine-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.