Description

2-Bromo-4-Chloro-3-Fluoro-Phenol is a halogenated phenolic compound serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its multi-halogenated structure makes it a critical building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials that require precise halogen substitution patterns.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Materials: Used in the production of halogenated aromatic cores for electronic display and lighting materials.
• Polymer Modification: Serves as a monomer or additive to introduce flame-retardant or other specific properties into polymer chains.
• Chemical Research & Development: A valuable reagent for exploring new coupling reactions and constructing complex heterocyclic frameworks in academic and industrial R&D.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized halogenated dyes and pigments.

Basic Information

Product Name	2-Bromo-4-Chloro-3-Fluoro-Phenol
CAS No.	1644281-89-9
Molecular Formula	C6H3BrClFO
Molecular Weight	225.44 g/mol
Synonyms	2-Bromo-4-chloro-3-fluorophenol; 3-Fluoro-2-bromo-4-chlorophenol; 4-Chloro-3-fluoro-2-bromophenol; Phenol, 2-bromo-4-chloro-3-fluoro-; 2-Br-4-Cl-3-F-PhOH
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloro-3-Fluoro-Phenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and ensures reliable integration into your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be kept under an inert atmosphere if long-term storage is required to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.