Description

4-Bromo-2-Iodo-5-Trifluoromethyl-Phenol is a halogenated phenol derivative with a trifluoromethyl substituent, serving as a versatile and high-value building block in advanced organic synthesis. Its unique structure, combining bromine, iodine, and fluorine atoms on an aromatic ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition and receptor modulation.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine and iodine atoms provide distinct reactivity for sequential Suzuki, Sonogashira, or Buchwald-Hartwig cross-coupling reactions, enabling complex molecular architectures.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or probes for studying biological pathways and protein interactions.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing halogenated phenolic motifs into target molecules in academic and industrial R&D settings.

Basic Information

Product Name	4-Bromo-2-Iodo-5-Trifluoromethyl-Phenol
CAS No.	1643916-11-3
Molecular Formula	C7H3BrF3IO
Molecular Weight	366.90 g/mol
Synonyms	2-Iodo-4-bromo-5-(trifluoromethyl)phenol; 5-(Trifluoromethyl)-4-bromo-2-iodophenol; 4-Bromo-2-iodo-α,α,α-trifluoro-m-cresol; Phenol, 4-bromo-2-iodo-5-(trifluoromethyl)-; 2-Iodo-4-bromo-α,α,α-trifluoro-m-cresol; 4-Bromo-2-iodo-5-trifluoromethylphenol; BITTFP
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Iodo-5-Trifluoromethyl-Phenol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.