Description

Di-tert-Butyl 2,5,8-Triazaspiro[3.5]Nonane-2,8-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic triaza scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecular architectures. It is primarily sought after by R&D teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders and other therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those requiring a rigid, three-dimensional spirocyclic core.
• Medicinal Chemistry Research: Used as a privileged scaffold in hit-to-lead optimization and structure-activity relationship (SAR) studies to improve potency and selectivity.
• API Development: Integral to the development pipeline for potential therapeutics in neurology, psychiatry, and oncology.
• Chemical Biology Probes: Serves as a starting material for creating specialized probes to study enzyme function and biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and new methodology development.

Basic Information

Product Name	Di-tert-Butyl 2,5,8-Triazaspiro[3.5]Nonane-2,8-Dicarboxylate
CAS No.	1639963-79-3
Molecular Formula	C17H31N3O4
Molecular Weight	341.45 g/mol
Synonyms	2,5,8-Triazaspiro[3.5]nonane-2,8-dicarboxylic acid, 1,1-dimethylethyl ester; Di-tert-butyl 2,5,8-triazaspiro[3.5]nonane-2,8-dicarboxylate; 2,8-Bis(tert-butoxycarbonyl)-2,5,8-triazaspiro[3.5]nonane; Boc-Protected 2,5,8-Triazaspiro[3.5]nonane; Spirocyclic Triaza Building Block; CAS 1639963-79-3
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl 2,5,8-Triazaspiro[3.5]Nonane-2,8-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for sensitive R&D applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.