Description

5-Bromo-6-Fluoro-1H-Indole-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its unique halogenated indole scaffold, which serves as a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in oncology, neurology, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated indole derivatives.

Basic Information

Product Name	5-Bromo-6-Fluoro-1H-Indole-3-Carboxylic Acid
CAS No.	1638772-16-3
Molecular Formula	C9H5BrFNO2
Molecular Weight	258.05 g/mol
Synonyms	5-Bromo-6-fluoroindole-3-carboxylic acid; 1H-Indole-3-carboxylic acid, 5-bromo-6-fluoro-; 5-Bromo-6-fluoro-1H-indole-3-carboxylate; 6-Fluoro-5-bromoindole-3-carboxylic acid; 1638772-16-3; 5-Br-6-F-1H-indole-3-COOH
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Fluoro-1H-Indole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.