Description

6-Methyl-2-Azaspiro[3.3]heptan-6-ol Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a unique spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemistry R&D and process development teams in the pharmaceutical and biotechnology industries seeking to develop next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its constrained spirocyclic scaffold.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the development of robust, scalable synthetic routes for API manufacturing.
• Bioconjugation & Probe Development: Potential utility in creating chemical probes or conjugates for biochemical and pharmacological studies.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic and pharmacological projects.

Basic Information

Product Name	6-Methyl-2-Azaspiro[3.3]heptan-6-ol Hydrochloride
CAS No.	1638765-02-2
Molecular Formula	C8H16ClNO
Molecular Weight	177.67 g/mol
Synonyms	6-Methyl-2-azaspiro[3.3]heptan-6-ol hydrochloride; 2-Azaspiro[3.3]heptan-6-ol, 6-methyl-, hydrochloride; 6-Methyl-2-azaspiro[3.3]heptane-6-ol HCl; 6-Methyl-2-azaspiro[3.3]heptan-6-ol HCl salt; 1638765-02-2; 6-Methyl-2-azaspiro[3.3]heptan-6-ol, hydrochloride; 6-Methyl-2-azaspiro[3.3]heptan-6-ol monohydrochloride
EINECS	Contact for details

Quality Control

Our 6-Methyl-2-Azaspiro[3.3]heptan-6-ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.