Description

2-(2,2,2-Trifluoroethyl)-2,6-Diazaspiro[3.3]Heptane is a high-value, nitrogen-containing spirocyclic building block featuring a trifluoroethyl substituent, prized for its unique three-dimensional structure and fluorine content. This compound is critical for medicinal chemistry research, enabling the rapid exploration of novel chemical space and the optimization of key drug-like properties such as metabolic stability, lipophilicity, and bioavailability. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of advanced intermediates for new therapeutic agents, particularly in central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key scaffold in the research and development of novel active pharmaceutical ingredients (APIs), especially for CNS and oncology applications.
• Medicinal Chemistry Building Block: Used to introduce a rigid, three-dimensional spirocyclic framework and fluorine atoms into lead compounds to modulate physicochemical and pharmacokinetic properties.
• Library Synthesis for Drug Discovery: Employed in high-throughput and parallel synthesis to create diverse compound libraries for biological screening.
• Ligand Development: Serves as a precursor for synthesizing sophisticated ligands used in catalysis or as probes in chemical biology.
• Agrochemical Research: Potential application in the development of new agrochemicals where the spirocyclic and fluorine motifs can enhance activity and environmental stability.
• Material Science Precursor: Can be utilized in the synthesis of advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or specialty polymers.

Basic Information

Product Name	2-(2,2,2-Trifluoroethyl)-2,6-Diazaspiro[3.3]Heptane
CAS No.	1638763-96-8
Molecular Formula	C9H13F3N2
Molecular Weight	206.21 g/mol
Synonyms	2,6-Diazaspiro[3.3]heptane, 2-(2,2,2-trifluoroethyl)-; 2-(2,2,2-Trifluoroethyl)-2,6-diazaspiro[3.3]heptane; 2,6-Diazaspiro[3.3]heptane, 2-(trifluoroethyl)-; 2-(Trifluoroethyl)-2,6-diazaspiro[3.3]heptane; 1638763-96-8; 2,6-Diazaspiro[3.3]heptane, 2-(2,2,2-trifluoroethyl)- (9CI); Spiro[3.3]heptane-2,6-diamine, N2-(2,2,2-trifluoroethyl)-
EINECS	Contact for details

Quality Control

Our production of 2-(2,2,2-Trifluoroethyl)-2,6-Diazaspiro[3.3]Heptane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Identity and purity are confirmed through a suite of analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.