Description

4'-Bromospiro[Cyclopropane-1,3'-Indolin]-2'-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic indolinone scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought after by R&D teams in the pharmaceutical, agrochemical, and fine chemical industries for creating new drug candidates and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents, particularly those targeting neurological disorders and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with new modes of action.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex spirocyclic and heterocyclic compounds.
• Chemical Biology Probe: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: An intermediate for the production of specialty chemicals, dyes, and functional materials.

Basic Information

Product Name	4'-Bromospiro[Cyclopropane-1,3'-Indolin]-2'-One
CAS No.	1637752-37-4
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	4'-Bromo-2-oxospiro[cyclopropane-1,3'-indoline]; 4'-Bromo-2,3-dihydrospiro[cyclopropane-1,3'-indol]-2'-one; 4'-Bromospiro[cyclopropane-1,3'-indolin]-2'-one; 4-Bromospiro[cyclopropane-1,3'-indolin]-2'-one; 4'-Bromo-2-oxospiro[cyclopropane-1,3'-indoline]; 4'-Bromospiro(cyclopropane-1,3'-indolin)-2'-one; 4'-Bromo-2,3-dihydrospiro[cyclopropane-1,3'-indol]-2-one; 4'-Bromo-2-oxospiro[cyclopropane-1,3'-indoline]
EINECS	Contact for details

Quality Control

Our 4'-Bromospiro[Cyclopropane-1,3'-Indolin]-2'-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.