Description

(R)-4-Methyl-Indan-1-Ylamine Hydrochloride is a high-purity chiral amine building block, essential for the synthesis of complex pharmaceutical intermediates. Its value lies in providing a stereochemically defined core structure, enabling the development of enantiomerically pure active pharmaceutical ingredients (APIs). This compound is critically needed by research and development chemists and process scale-up teams within the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Synthesis: Serves as a versatile building block in the construction of complex molecules requiring the (R)-configured amine moiety.
• Agrochemical Research: Used in the synthesis of chiral active ingredients for crop protection products, where specific stereochemistry can influence biological activity.
• Catalyst and Ligand Preparation: Potential precursor for the synthesis of chiral catalysts and ligands used in enantioselective transformations.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic and Contract Research: Utilized in academic laboratories and CROs (Contract Research Organizations) for exploratory chemistry and process optimization studies.

Basic Information

Product Name	(R)-4-Methyl-Indan-1-Ylamine Hydrochloride
CAS No.	1637453-78-1
Molecular Formula	C11H16ClN
Molecular Weight	197.70 g/mol
Synonyms	(1R)-4-Methyl-2,3-dihydro-1H-inden-1-amine hydrochloride; (R)-1-Amino-4-methylindane hydrochloride; (R)-4-Methyl-1-indanamine hydrochloride; (R)-4-Methylindan-1-amine HCl; (R)-4-Methyl-2,3-dihydro-1H-inden-1-amine hydrochloride; 1H-Inden-1-amine, 4-methyl-2,3-dihydro-, (1R)-, hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-4-Methyl-Indan-1-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.