Description

(R)-5-Chloro-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a stereochemically defined core for constructing complex molecules, ensuring precise pharmacological activity in final products. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• API Development: Serves as a foundational building block in the synthetic pathway of potential Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Employed in the synthesis of chiral pesticides and herbicides where specific stereochemistry is required for bioactivity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Catalyst Ligand Precursor: Can be modified to form ligands for asymmetric catalysis in industrial chemical processes.

Basic Information

Product Name	(R)-5-Chloro-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride
CAS No.	1637453-67-8
Molecular Formula	C9H11Cl2N
Molecular Weight	204.10 g/mol
Synonyms	(1R)-5-Chloro-2,3-dihydro-1H-inden-1-amine hydrochloride; (R)-5-Chloroindan-1-amine hydrochloride; (R)-1-Amino-5-chloroindane hydrochloride; 5-Chloro-(1R)-indan-1-amine hydrochloride; (R)-5-Chloro-1-indanamine hydrochloride; (1R)-5-Chloro-1-indanamine hydrochloride; UNII-9Q3L5F1Q8F; (R)-5-Chloro-2,3-dihydro-1H-inden-1-amine HCl
EINECS	Contact for details

Quality Control

Every batch of (R)-5-Chloro-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including HPLC, NMR, and chiral purity data, to ensure the product meets rigorous research and development standards. A Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (ee), and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.