Description

2-Thia-6-Aza-Spiro[3.3]Heptane2,2-Dioxide Trifluoroacetate (Wx100440S3) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic sulfonamide scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical and biotechnology companies for use in drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to develop new drug candidates.
• Proteolysis Targeting Chimera (PROTAC) Development: The spirocyclic structure can serve as a versatile linker or component in the design of bifunctional degraders.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.

Basic Information

Product Name	2-Thia-6-Aza-Spiro[3.3]Heptane2,2-Dioxide Trifluoroacetate (Wx100440S3)
CAS No.	1636128-26-1
Molecular Formula	C7H8F3N O4S
Molecular Weight	259.20 g/mol
Synonyms	2-Thia-6-azaspiro[3.3]heptane 2,2-dioxide trifluoroacetate; 6-Aza-2-thiaspiro[3.3]heptane 2,2-dioxide trifluoroacetate salt; 2-Thia-6-aza-spiro[3.3]heptane-2,2-dioxide, trifluoroacetic acid salt; WX100440S3; WX-100440S3; 1636128-26-1; Spirocyclic sulfonamide trifluoroacetate
EINECS	Contact for details

Quality Control

Our 2-Thia-6-Aza-Spiro[3.3]Heptane2,2-Dioxide Trifluoroacetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.