Description

2-((2-Aminopyrimidin-4-Yl)Oxy)-n-(3-(Trifluoromethyl)Phenyl)Quinoline-5-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for research and development in targeted drug discovery. This compound matters for its role as a key building block in the synthesis of novel kinase inhibitors and other biologically active molecules, offering researchers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and contract research organizations (CROs) focused on oncology, inflammation, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of investigational new drugs (INDs), particularly kinase inhibitors.
• Biochemical Research: Used as a reference standard or a ligand in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Medicinal Chemistry: Serves as a core scaffold for the development of novel small-molecule therapeutics targeting specific disease pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions for clinical trial material production.

Basic Information

Product Name	2-((2-Aminopyrimidin-4-Yl)Oxy)-n-(3-(Trifluoromethyl)Phenyl)Quinoline-5-Carboxamide
CAS No.	1631035-78-3
Molecular Formula	C21H14F3N5O2
Molecular Weight	425.36 g/mol
Synonyms	2-[(2-Aminopyrimidin-4-yl)oxy]-N-[3-(trifluoromethyl)phenyl]quinoline-5-carboxamide; 2-((2-Aminopyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)quinoline-5-carboxamide; 1631035-78-3; Quinoline-5-carboxamide, 2-((2-amino-4-pyrimidinyl)oxy)-N-(3-(trifluoromethyl)phenyl)-; UNII-7F0C3W6T7I; 7F0C3W6T7I
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. We adhere to strict quality management protocols suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.