Description

Methyl trans-3-Aminobicyclo[2.2.2]Octane-2-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a rigid bicyclic scaffold. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and neurological research. It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers for developing new therapeutic agents and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained 3D geometry.
• Organic Synthesis: Serves as a chiral, bicyclic amine component in asymmetric synthesis and the construction of complex molecular architectures.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in API manufacturing.
• Bioconjugation & Probe Development: Potential use in creating biochemical probes and labeled compounds for diagnostic applications.

Basic Information

Product Name	Methyl trans-3-Aminobicyclo[2.2.2]Octane-2-Carboxylate Hydrochloride
CAS No.	1630906-99-8
Molecular Formula	C10H18ClNO2
Molecular Weight	219.71 g/mol
Synonyms	Methyl (1R,2S,4S)-3-Aminobicyclo[2.2.2]octane-2-carboxylate hydrochloride; Methyl 3-aminobicyclo[2.2.2]octane-2-carboxylate HCl; trans-3-Amino-2-bicyclo[2.2.2]octanecarboxylic acid methyl ester hydrochloride; Bicyclo[2.2.2]octane-2-carboxylic acid, 3-amino-, methyl ester, hydrochloride, (1R,2S,4S)-; 1630906-99-8; Methyl 3-aminobicyclo[2.2.2]octane-2-carboxylate hydrochloride; (1R,2S,4S)-Methyl 3-aminobicyclo[2.2.2]octane-2-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl trans-3-Aminobicyclo[2.2.2]Octane-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.