Description

tert-Butyl 4-[3-(Methanesulfonyloxy)Propyl]Piperazine-1-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate of significant importance in modern synthetic chemistry. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially in medicinal chemistry research and development.
• API Synthesis: Serves as a key building block for constructing active pharmaceutical ingredients (APIs) with piperazine and sulfonate ester functionalities.
• Neurological Drug Development: Used in the research and production of compounds targeting neurological receptors and pathways.
• Chemical Research: Employed in academic and industrial laboratories for method development and the synthesis of novel chemical entities.
• Process Chemistry: Utilized in process optimization and scale-up studies for efficient and cost-effective manufacturing routes.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group provides a versatile protecting strategy for amine functionalities during complex syntheses.

Basic Information

Product Name	tert-Butyl 4-[3-(Methanesulfonyloxy)Propyl]Piperazine-1-Carboxylate Hydrochloride
CAS No.	1630906-98-7
Molecular Formula	C13H27ClN2O5S
Molecular Weight	358.88 g/mol
Synonyms	1-Boc-4-(3-(methylsulfonyloxy)propyl)piperazine hydrochloride; tert-Butyl 4-(3-((methylsulfonyl)oxy)propyl)piperazine-1-carboxylate hydrochloride; 1-(tert-Butoxycarbonyl)-4-[3-(methanesulfonyloxy)propyl]piperazine hydrochloride; 4-(3-(Methanesulfonyloxy)propyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester hydrochloride; Boc-4-(3-(methylsulfonyloxy)propyl)piperazine HCl; 1630906-98-7; Piperazine, 4-[3-[(methylsulfonyl)oxy]propyl]-, 1-(1,1-dimethylethyl) 1-carboxylate, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[3-(Methanesulfonyloxy)Propyl]Piperazine-1-Carboxylate Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.