Description

2,6-Diazaspiro[3.4]Octane Dihydrochloride is a high-value, spirocyclic building block and intermediate of significant interest in modern pharmaceutical research and development. Its unique constrained bicyclic structure makes it a privileged scaffold for designing novel drug candidates, particularly in medicinal chemistry programs. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new therapeutic agents, especially for central nervous system (CNS) and metabolic disease targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve the pharmacokinetic properties of lead compounds.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a linker or core component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Utilized in the development of tool compounds to study biological pathways and target validation.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.

Basic Information

Product Name	2,6-Diazaspiro[3.4]Octane Dihydrochloride
CAS No.	1630906-93-2
Molecular Formula	C6H14Cl2N2
Molecular Weight	185.10 g/mol
Synonyms	2,6-Diazaspiro[3.4]octane, 2HCl; Spiro[3.4]octane-2,6-diamine dihydrochloride; 2,6-Diazaspiro[3.4]octane dihydrochloride; 2,6-Diaza-spiro[3.4]octane hydrochloride; 1630906-93-2; 2,6-Diazaspiro[3.4]octane hydrochloride; 2,6-Diazaspiro[3.4]octane HCl
EINECS	Contact for details

Quality Control

Our 2,6-Diazaspiro[3.4]Octane Dihydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development applications. All batches are analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.