Description

tert-Butyl 2,5-Diazaspiro[3.4]Octane-5-Carboxylate Hemioxalate is a high-value, advanced pharmaceutical intermediate featuring a constrained spirocyclic diamine scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel drug candidates with improved metabolic stability and target selectivity. It is primarily utilized by pharmaceutical companies and research organizations engaged in the discovery of small molecule therapeutics, particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component for constructing linkers or ligands in bifunctional degrader molecules.
• CNS Drug Discovery: The spirocyclic diamine structure is valuable for creating compounds designed to cross the blood-brain barrier.
• Kinase Inhibitor Synthesis: Employed in the development of selective kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Used to create tool compounds for studying biological processes and target validation.

Basic Information

Product Name	tert-Butyl 2,5-Diazaspiro[3.4]Octane-5-Carboxylate Hemioxalate
CAS No.	1630906-60-3
Molecular Formula	C11H20N2O2 • 0.5C2H2O4
Molecular Weight	Contact for details
Synonyms	2,5-Diazaspiro[3.4]octane-5-carboxylic acid, 1,1-dimethylethyl ester, hemioxalate; 5-Boc-2,5-diazaspiro[3.4]octane hemioxalate salt; tert-Butyl 2,5-diazaspiro[3.4]octane-5-carboxylate oxalic acid salt (1:0.5); 5-(tert-Butoxycarbonyl)-2,5-diazaspiro[3.4]octane hemioxalate; Boc-2,5-diazaspiro[3.4]octane hemioxalate; 1630906-60-3; Spiro[3.4]octane-2,5-diamine, N5-Boc-protected hemioxalate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,5-Diazaspiro[3.4]Octane-5-Carboxylate Hemioxalate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Single Unknown Impurity	≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.