Description

tert-Butyl 6-Methylidene-2-Azaspiro[3.3]heptane-2-carboxylate is a sophisticated spirocyclic building block and protected amine intermediate of significant interest in advanced organic synthesis. Its unique, rigid three-dimensional structure makes it a valuable scaffold for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring constrained molecular architectures.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides with potentially improved efficacy and environmental profiles.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study biological pathways and protein functions.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: A versatile tool for methodological development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	tert-Butyl 6-Methylidene-2-Azaspiro[3.3]heptane-2-Carboxylate
CAS No.	1630906-30-7
Molecular Formula	C12H19NO2
Molecular Weight	209.28 g/mol
Synonyms	2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-methylene-, 1,1-dimethylethyl ester; 6-Methylene-2-azaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester; tert-Butyl 6-methylidene-2-azaspiro[3.3]heptane-2-carboxylate; 2-tert-Butoxycarbonyl-6-methylidene-2-azaspiro[3.3]heptane; BOC-6-Methylidene-2-azaspiro[3.3]heptane; 6-Methylene-2-Boc-2-azaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Methylidene-2-Azaspiro[3.3]heptane-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.