Description

2-((Diphenylmethylene)Amino)Propane-1,3-Diol is a specialized organic compound featuring a diphenylmethylene-protected amino diol structure, serving as a valuable chiral building block and intermediate in advanced synthesis. Its core value lies in enabling the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. This high-purity intermediate is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry studies within university and corporate research laboratories.
• Peptidomimetic Scaffolds: The amino diol moiety can be incorporated into peptidomimetic structures for drug discovery programs targeting protein-protein interactions.

Basic Information

Product Name	2-((Diphenylmethylene)Amino)Propane-1,3-Diol
CAS No.	1624261-16-0
Molecular Formula	C16H17NO2
Molecular Weight	255.31 g/mol
Synonyms	1,3-Propanediol, 2-[(diphenylmethylene)amino]-; 2-(Diphenylmethylideneamino)propane-1,3-diol; 2-[(Diphenylmethylene)amino]-1,3-propanediol; (Diphenylmethyleneamino)propane-1,3-diol; Amino Diol Diphenylmethylene Acetal; N-(Diphenylmethylene)-2-amino-1,3-propanediol; Chiral Amino Diol Intermediate; Protected Amino Diol Synthon
EINECS	Contact for details

Quality Control

Our 2-((Diphenylmethylene)Amino)Propane-1,3-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.