Description

S-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol is a high-value, enantiomerically pure binaphthol derivative, a crucial chiral ligand and building block in asymmetric synthesis. Its core value lies in its ability to induce high stereoselectivity in catalytic reactions, enabling the production of optically active compounds with superior efficiency. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise chiral control for developing novel active ingredients and functional molecules.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, C-C bond formation, and oxidation.
• As a key precursor for synthesizing more complex chiral catalysts and auxiliaries.
• In the research and development of pharmaceutical intermediates and active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• For the synthesis of agrochemicals where enantiopurity impacts biological activity and environmental safety.
• In the development of chiral stationary phases (CSPs) for analytical and preparative chromatography.
• As a building block for functional organic materials, such as chiral polymers and liquid crystals.

Basic Information

Product Name	S-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol
CAS No.	1621066-21-4
Molecular Formula	C34H20F6O2
Molecular Weight	574.52 g/mol
Synonyms	(S)-3,3'-Bis[4-(trifluoromethyl)phenyl]-1,1'-binaphthalene-2,2'-diol; (S)-3,3'-Bis(4-trifluoromethylphenyl)-BINOL; (S)-3,3'-Di(4-trifluoromethylphenyl)-1,1'-bi-2-naphthol; S-3,3'-Bis(4-(trifluoromethyl)phenyl)-BINOL; S-3,3'-Bis(p-trifluoromethylphenyl)-BINOL; (S)-3,3'-Bis(4-trifluoromethylphenyl)-2,2'-dihydroxy-1,1'-binaphthyl; (S)-3,3'-Bis(4-(Trifluoromethyl)phenyl)-[1,1'-Binaphthalene]-2,2'-diol
EINECS	Contact for details

Quality Control

Our S-3,3'-Bis[4-(Trifluoromethyl)Phenyl]-[1,1'-Binaphthalene]-2,2'-Diol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess (ee), and impurity profile is provided with every shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.