Description

3-Bromo-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethyl substituents on the quinoline core, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and the development of anti-infective or anti-cancer agents.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Research: Serves as a building block for creating organic semiconductors, light-emitting diodes (OLEDs), and other functional organic electronic materials.
• Ligand and Catalyst Development: The bromine atom provides a versatile handle for cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex chelating ligands for catalysis.
• Fluorine Chemistry Studies: An important substrate for investigating the influence of the trifluoromethyl group on reaction pathways and molecular properties.
• Chemical Library Synthesis: Employed in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	3-Bromo-2-(Trifluoromethyl)Quinoline
CAS No.	1620749-79-2
Molecular Formula	C₁₀H₅BrF₃N
Molecular Weight	276.05 g/mol
Synonyms	3-Bromo-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-3-bromoquinoline; Quinoline, 3-bromo-2-(trifluoromethyl)-; 3-Bromo-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.