Description

4-(Bromoethynyl)Benzoic Acid is a high-purity, multi-functional organic building block featuring a benzoic acid core functionalized with a bromoethynyl group. This unique structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging its reactive ethynyl group for structural diversification.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe Development: Utilized in click chemistry and bioconjugation strategies to attach labels or functional groups to biomolecules for diagnostic and research applications.
• Organic Synthesis Reagent: Employed in Sonogashira coupling and other palladium-catalyzed cross-coupling reactions to introduce aromatic acetylene functionalities.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploratory synthesis in university and corporate research laboratories.

Basic Information

Product Name	4-(Bromoethynyl)Benzoic Acid
CAS No.	1617498-10-8
Molecular Formula	C9H5BrO2
Molecular Weight	225.04 g/mol
Synonyms	4-(2-Bromoethynyl)benzoic acid; p-(Bromoethynyl)benzoic acid; Benzoic acid, 4-(bromoethynyl)-; 4-Ethynylbenzoic acid, 2-bromo derivative; (4-Carboxyphenyl)ethynyl bromide; 2-Bromo-1-(4-carboxyphenyl)ethyne; 4-(Bromoethynyl)benzenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(Bromoethynyl)Benzoic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.