Description

2,2-Dimethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-boronic acid is a high-value, multifunctional heterocyclic boronic acid derivative. This compound serves as a critical building block in modern synthetic chemistry, enabling the formation of carbon-carbon and carbon-heteroatom bonds via cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex drug candidates, particularly those containing the benzoxazine scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and novel polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Academic & Contract Research: Essential for methodological development in organic synthesis and discovery chemistry within R&D laboratories.

Basic Information

Product Name	2,2-Dimethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-boronic acid
CAS No.	1613450-45-5
Molecular Formula	C10H12BNO4
Molecular Weight	221.02 g/mol
Synonyms	6-Borono-2,2-dimethyl-2,3-dihydro-4H-1,4-benzoxazin-3-one; 2,2-Dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-boronic acid; 2,2-Dimethyl-3-oxo-2,3-dihydro-4H-benzo[b][1,4]oxazine-6-boronic acid; 6-Boronic acid-2,2-dimethyl-4H-1,4-benzoxazin-3-one; B-(2,2-Dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)boronic acid
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-boronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and elemental analysis to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.