Description

Palladium, [1,3-Bis[2,6-Bis(1-Ethylpropyl)Phenyl]-4,5-Dichloro-1,3-Dihydro-2H-Imidazol-2-Ylidene]Dichloro(2-Methylpyridine)-, (Sp-4-1)- is a highly specialized, air-stable N-heterocyclic carbene (NHC) palladium(II) complex designed for advanced catalytic applications. This compound matters because it offers superior thermal stability and tunable steric bulk, enabling challenging cross-coupling reactions under mild conditions with high turnover numbers. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new synthetic routes and scaling up production of complex organic molecules.

Application

• Pharmaceutical Intermediate Synthesis: Catalyst for key C-C and C-N bond-forming reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination) in API development.
• Agrochemical Research: Enabling the synthesis of novel, complex active ingredients with improved efficacy and selectivity.
• Polymer & Material Science: Facilitating controlled polymerization reactions and the synthesis of functionalized monomers for specialty polymers.
• Academic & Industrial R&D: A versatile pre-catalyst for methodological development in organic synthesis and catalysis studies.
• Fine Chemical Production: Used in the multi-step synthesis of flavors, fragrances, and electronic chemicals where high selectivity is required.
• Ligand Screening Libraries: Serves as a benchmark or component in high-throughput screening for new catalytic systems.

Basic Information

Product Name	Palladium, [1,3-Bis[2,6-Bis(1-Ethylpropyl)Phenyl]-4,5-Dichloro-1,3-Dihydro-2H-Imidazol-2-Ylidene]Dichloro(2-Methylpyridine)-, (Sp-4-1)-
CAS No.	1612891-29-8
Molecular Formula	C44H60Cl4N3Pd
Molecular Weight	889.67 g/mol
Synonyms	Palladium(II) (1,3-Bis(2,6-bis(1-ethylpropyl)phenyl)-4,5-dichloroimidazol-2-ylidene)(2-methylpyridine) dichloride; (SIPr)Pd(2-MePy)Cl2; Dichloro[1,3-bis[2,6-bis(1-ethylpropyl)phenyl]-4,5-dichloro-2-imidazolylidene](2-methylpyridine)palladium; Palladium SIPr 2-methylpyridine complex; NHC-Pd(II)-2-Picoline Complex; (SP-4-1)-Dichloro[1,3-bis(2,6-di(1-ethylpropyl)phenyl)-4,5-dichloro-2-imidazolylidene](2-methylpyridine-κN)palladium
EINECS	Contact for details

Quality Control

Our organometallic catalysts are manufactured under stringent quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes comprehensive analysis including NMR (1H, 13C), elemental analysis (CHN), and HPLC purity determination to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain long-term stability. This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Palladium (Pd) Content	11.5 - 12.5 %
Elemental Analysis (C, H, N)	Within ± 0.4% of theoretical
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.