Description

2-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is valued for its rigid, spirocyclic diaza scaffold, which is crucial for modulating the physicochemical and biological properties of drug candidates in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of novel therapeutic agents, particularly within central nervous system (CNS) and other small molecule drug programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of bioactive molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Library Synthesis: Employed for the construction of diverse compound libraries for high-throughput screening (HTS).
• CNS Drug Discovery: The spirocyclic diamine structure is pertinent for targeting neurological receptors and enzymes.
• Chemical Biology: Serves as a scaffold or linker in the development of chemical probes and tools.
• Process Chemistry Development: Used in route scouting and scale-up studies for potential drug candidates.

Basic Information

Product Name	2-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride
CAS No.	1610028-42-6
Molecular Formula	C9H18N2·2HCl
Molecular Weight	239.17 g/mol
Synonyms	2-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride; 2-Methyl-2,7-diazaspiro[3.5]nonane hydrochloride; 2-Methyl-2,7-diazaspiro[3.5]nonane HCl; 2-Methyl-2,7-diazaspiro[3.5]nonane, dihydrochloride; 2-Methyl-2,7-diazaspiro[3.5]nonane, hydrochloride (1:2); 2,7-Diazaspiro[3.5]nonane, 2-methyl-, dihydrochloride; 1610028-42-6
EINECS	Contact for details

Quality Control

Our 2-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.