Description

n-(2-Amino-5-(Thiophen-2-Yl)Phenyl)-2-(Piperazin-1-Yl)Quinoline-6-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for research and development in medicinal chemistry. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of novel kinase inhibitors due to its quinoline and piperazine motifs.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological processes and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	n-(2-Amino-5-(Thiophen-2-Yl)Phenyl)-2-(Piperazin-1-Yl)Quinoline-6-Carboxamide
CAS No.	1609389-52-7
Molecular Formula	C24H23N5OS
Molecular Weight	437.54 g/mol
Synonyms	2-(Piperazin-1-yl)-N-[2-amino-5-(thiophen-2-yl)phenyl]quinoline-6-carboxamide; 1609389-52-7; Quinoline-6-carboxamide, N-[2-amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)-; N-(2-Amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide; 2-Piperazin-1-yl-N-[2-amino-5-(thiophen-2-yl)phenyl]quinoline-6-carboxamide
EINECS	Contact for details

Quality Control

Our n-(2-Amino-5-(Thiophen-2-Yl)Phenyl)-2-(Piperazin-1-Yl)Quinoline-6-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.