Description

(But-3-Yn-1-Yl)(2,2,2-Trifluoroethyl)Amine Hydrochloride is a high-purity, specialized organic building block featuring both an alkyne and a trifluoroethylamine moiety. This compound is valued for its role as a key intermediate in advanced pharmaceutical and agrochemical synthesis, enabling the introduction of unique structural motifs. It is primarily utilized by research and development chemists in the life sciences sector for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Chemical Biology Probe Synthesis: The alkyne handle allows for efficient conjugation via click chemistry (e.g., CuAAC) to create labeled probes for target identification and binding studies.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with tailored surface properties.
• Ligand Development for Catalysis: Employed in the preparation of novel nitrogen-containing ligands for transition metal catalysis.

Basic Information

Product Name	(But-3-Yn-1-Yl)(2,2,2-Trifluoroethyl)Amine Hydrochloride
CAS No.	1607287-84-2
Molecular Formula	C7H9ClF3N
Molecular Weight	199.60 g/mol
Synonyms	N-(But-3-yn-1-yl)-2,2,2-trifluoroethanamine hydrochloride; 2,2,2-Trifluoro-N-(3-butynyl)ethanamine hydrochloride; 3-Butyn-1-amine, N-(2,2,2-trifluoroethyl)-, hydrochloride; 4-Pentynamine, N-(2,2,2-trifluoroethyl)-, hydrochloride; (But-3-ynyl)(2,2,2-trifluoroethyl)amine HCl; Trifluoroethylbutynylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (But-3-Yn-1-Yl)(2,2,2-Trifluoroethyl)Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.