Description

T-Buxphos Palladacycle Gen. 4 is a highly active, fourth-generation palladium-based precatalyst designed for demanding cross-coupling reactions. Its advanced ligand architecture provides exceptional stability and reactivity, enabling efficient synthesis under mild conditions. This catalyst is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries seeking robust and scalable solutions for C-C and C-N bond formation.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key Suzuki-Miyaura, Buchwald-Hartwig, and other cross-coupling reactions in API development.
• Agrochemical Manufacturing: Facilitating the construction of complex heterocyclic compounds for crop protection agents.
• Materials Science Research: Used in the synthesis of conjugated polymers, organic semiconductors, and advanced ligands.
• Process Chemistry & Scale-up: Valued for its consistent performance and lower catalyst loadings in pilot and production-scale reactions.
• Academic & Industrial R&D: A preferred precatalyst for methodological development and exploring new chemical space in peer-reviewed and proprietary research.

Basic Information

Product Name	T-Buxphos Palladacycle Gen. 4
CAS No.	1599466-89-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Palladacycle T-Buxphos Gen. 4; T-Buxphos Pd G4; Fourth-Generation T-Buxphos Palladacycle; Chloro[(di-tert-butylphosphino)-2-(2,4,6-triisopropylphenyl)phenyl]palladium(II); Buchwald Palladacycle Gen. 4 T-Buxphos; Pd-Precatalyst T-Buxphos G4; Palladium(II) T-Buxphos Chloride Complex
EINECS	Contact for details

Quality Control

Every batch of T-Buxphos Palladacycle Gen. 4 is manufactured and tested under strict quality management protocols to ensure high catalytic activity and lot-to-lot consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and performance metrics are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place (15-25°C). Due to its moisture-sensitive and easily oxidized nature, the container should only be opened in a controlled, dry environment and resealed immediately after use.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Palladium (Pd) Content	Contact for details
Solubility	Soluble in common organic solvents (e.g., THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.