Description

2'-Chloro-3,4-Dihydro-[1,1'-Biphenyl]-1(2H)-Ol is a specialized organic intermediate featuring a chlorinated biphenyl core fused with a partially reduced ring system. This compound matters for its role as a versatile chiral building block in the synthesis of complex, biologically active molecules, offering chemists a handle for further functionalization. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Serves as a precursor in the design and production of advanced herbicides and fungicides, leveraging its halogenated biphenyl structure.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Investigated as a monomer or precursor for advanced polymers and liquid crystalline materials due to its rigid, aromatic backbone.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	2'-Chloro-3,4-Dihydro-[1,1'-Biphenyl]-1(2H)-Ol
CAS No.	1599155-96-0
Molecular Formula	C12H13ClO
Molecular Weight	208.68 g/mol
Synonyms	1(2H)-Biphenylol, 2'-chloro-3,4-dihydro-; 2'-Chloro-1,2,3,4-tetrahydro-[1,1'-biphenyl]-1-ol; 2'-Chloro-3,4-dihydro-1,1'-biphenyl-1(2H)-one (tautomer); 2'-Chloro-α-tetralol; (2'-Chlorobiphenyl-1-yl)methanol (reduced form); 1-Hydroxy-2'-chloro-1,2,3,4-tetrahydrobiphenyl
EINECS	Contact for details

Quality Control

Our 2'-Chloro-3,4-Dihydro-[1,1'-Biphenyl]-1(2H)-Ol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your compliance and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.