Description

8-Fluoro-2-Mercaptoquinazolin-4(3H)-One 95+% is a high-purity, fluorinated quinazolinone derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile scaffold in medicinal chemistry, enabling the development of novel pharmaceutical candidates. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery of new therapeutic agents, particularly for applications in oncology and targeted drug development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential herbicidal or fungicidal properties.
• Chemical Biology Probes: Utilized in the development of fluorescent or affinity probes to study biological pathways and protein functions.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique electronic or optical properties.

Basic Information

Product Name	8-Fluoro-2-Mercaptoquinazolin-4(3H)-One 95+%
CAS No.	1597549-01-3
Molecular Formula	C₈H₅FN₂OS
Molecular Weight	196.20 g/mol
Synonyms	8-Fluoro-4-hydroxy-2-mercaptoquinazoline; 8-Fluoro-2-sulfanyl-3,4-dihydroquinazolin-4-one; 8-Fluoro-2-thioxo-1,2-dihydroquinazolin-4(3H)-one; 8-Fluoro-2-mercapto-4(3H)-quinazolinone; 8-Fluoro-2-thioquinazolin-4-one; 1597549-01-3; 8-Fluoro-2-mercapto-3H-quinazolin-4-one
EINECS	Contact for details

Quality Control

Our 8-Fluoro-2-Mercaptoquinazolin-4(3H)-One 95+% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/LC-MS for structural confirmation, to ensure it meets the specified 95+% purity grade. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, prolonged exposure to light, air, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.