Description

4-Bromo-1-Chloro-2,7-Naphthyridine is a high-purity, halogenated naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique fused heterocyclic structure, which provides a versatile scaffold for constructing complex molecules with tailored properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used to construct active components for crop protection agents, leveraging its halogenated structure for further functionalization.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Employed in the development of fluorescent tags or molecular probes due to the naphthyridine core's potential photophysical properties.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for sequential palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Library Synthesis: A valuable starting material for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	4-Bromo-1-Chloro-2,7-Naphthyridine
CAS No.	1588569-14-5
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	1-Chloro-4-bromo-2,7-naphthyridine; 4-Bromo-1-chloro-2,7-naphthyridine; 2,7-Naphthyridine, 4-bromo-1-chloro-; 1588569-14-5; 4-Bromo-1-chloro-2,7-naphthyridine; 1-Chloro-4-bromo-2,7-naphthyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-1-Chloro-2,7-Naphthyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.