Description

2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine] Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is of significant value for its role as a key synthetic precursor in modern medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new drug candidates, particularly within the fields of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Chemical Synthesis: Serves as a versatile spirocyclic scaffold for constructing novel heterocyclic compounds with potential biological activity.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for exploratory synthetic projects.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine] Dihydrochloride
CAS No.	1588441-25-1
Molecular Formula	C13H18Cl2N2
Molecular Weight	273.20 g/mol
Synonyms	1',2',3',4'-Tetrahydrospiro[piperidine-4,4'-isoquinoline] dihydrochloride; Spiro[piperidine-4,4'-isoquinoline] dihydrochloride; 2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine] hydrochloride (1:2); 1,2,3,4-Tetrahydrospiro[isoquinoline-4,4'-piperidine] dihydrochloride
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine] Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.