Description

(6S,12Ar)-3,10-Dibromo-6-Phenyl-12,12A-Dihydro-6H-Benzo[5,6][1,3]Oxazino[3,4-A]Indole is a high-purity, advanced pharmaceutical intermediate featuring a complex fused heterocyclic structure with bromine substituents. This compound is of significant value for medicinal chemistry research and development, serving as a key building block in the synthesis of novel bioactive molecules. It is primarily sought by R&D teams and process chemists in the pharmaceutical and biotechnology industries for the development of new therapeutic agents, particularly those targeting central nervous system disorders or oncological pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic compounds.
• Organic Synthesis Building Block: Employed in the construction of complex polycyclic frameworks due to its reactive bromine sites and rigid indole-oxazine scaffold.
• Chemical Biology Probes: Potential use in the development of molecular probes for studying biological pathways and target engagement.
• Process Development & Scale-Up: Serves as a reference standard and starting material for optimizing synthetic routes from lab to pilot plant scale.

Basic Information

Product Name	(6S,12Ar)-3,10-Dibromo-6-Phenyl-12,12A-Dihydro-6H-Benzo[5,6][1,3]Oxazino[3,4-A]Indole
CAS No.	1585969-16-9
Molecular Formula	C24H16Br2N2O
Molecular Weight	508.21 g/mol
Synonyms	3,10-Dibromo-6-phenyl-12,12a-dihydro-6H-benzo[5,6][1,3]oxazino[3,4-a]indole; (6S,12aR)-3,10-Dibromo-6-phenyl-12,12a-dihydro-6H-benzo[5,6][1,3]oxazino[3,4-a]indole; Benzoxazinoindole dibromo derivative; CAS 1585969-16-9; 1585969-16-9
EINECS	Contact for details

Quality Control

Our (6S,12Ar)-3,10-Dibromo-6-Phenyl-12,12A-Dihydro-6H-Benzo[5,6][1,3]Oxazino[3,4-A]Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting research-grade standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.