Description

Tertbutyl 5Oxo2Azaspiro[3.4]Octane2Carboxylate is a high-value, advanced pharmaceutical intermediate belonging to the spirocyclic lactam class of compounds. Its unique and complex spiro-fused bicyclic structure makes it a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by research and development organizations and fine chemical manufacturers within the global life sciences sector.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Protease Inhibitor Research: Serves as a core scaffold for developing novel inhibitors of proteolytic enzymes, relevant for antiviral and anticancer therapies.
• Medicinal Chemistry: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke, multi-step synthetic routes.
• Chemical Biology: Utilized as a molecular probe or tool compound to study biological pathways and protein function.

Basic Information

Product Name	Tertbutyl 5Oxo2Azaspiro[3.4]Octane2Carboxylate
CAS No.	1581683-57-9
Molecular Formula	C12H19NO3
Molecular Weight	225.28 g/mol
Synonyms	tert-Butyl 5-oxo-2-azaspiro[3.4]octane-2-carboxylate; 2-Azaspiro[3.4]octane-2-carboxylic acid, 5-oxo-, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-2-azaspiro[3.4]octan-5-one; Boc-2-azaspiro[3.4]octan-5-one; 5-Oxo-2-azaspiro[3.4]octane-2-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of Tertbutyl 5Oxo2Azaspiro[3.4]Octane2Carboxylate adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.