Description

Bicyclo[1.1.1]Pentan-1-Aminehydrochloride CAS NO 1581682-06-5 is a high-value, strained organic building block featuring the unique [1.1.1]propellane core structure. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where its rigid, three-dimensional geometry is highly sought after. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, biotechnology, and material science industries to create complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bioactive molecules and active pharmaceutical ingredients (APIs), especially for drug discovery programs targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used to construct novel pesticide and herbicide candidates with potentially enhanced activity and environmental profiles.
• Material Science: Serves as a building block for creating polymers and advanced materials with unique mechanical or optical properties derived from its strained cage structure.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Incorporated into linker molecules and warheads for the development of targeted protein degradation therapeutics.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, particularly in cross-coupling and C-H functionalization reactions.
• Ligand Synthesis: Used to prepare novel ligands for catalysis, potentially leading to more efficient and selective catalytic processes.

Basic Information

Product Name	Bicyclo[1.1.1]Pentan-1-Aminehydrochloride
CAS No.	1581682-06-5
Molecular Formula	C5H10ClN
Molecular Weight	119.59 g/mol
Synonyms	1-Aminobicyclo[1.1.1]pentane hydrochloride; [1.1.1]Propellane-1-amine hydrochloride; BCP-NH2·HCl; 1-Azabicyclo[1.1.1]pentane hydrochloride (common misnomer); 1-Bicyclo[1.1.1]pentanylaminium chloride; BCP amine HCl; 1-Amino[1.1.1]propellane hydrochloride
EINECS	Contact for details

Quality Control

Our Bicyclo[1.1.1]Pentan-1-Aminehydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be kept tightly sealed in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.