Description

2-Amino-5-(n-Boc-Piperidin-3-Yl)Pyridine is a high-purity, protected piperidine-pyridine hybrid building block essential for modern pharmaceutical research and development. This compound matters as a critical intermediate in the synthesis of complex small molecule drugs, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. Pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers need this advanced intermediate for constructing novel drug candidates with high stereochemical and functional group fidelity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for neurological and psychiatric drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the 3-(Boc-piperidinyl)pyridine scaffold into candidate molecules.
• Protease Inhibitor Development: Serves as a precursor for compounds targeting various protease enzymes due to its amine and protected amine functionalities.
• Kinase Inhibitor Synthesis: Employed in the construction of heterocyclic cores for potential kinase inhibitors in oncology research.
• Chemical Biology Probes: Utilized to create tool compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) performing custom synthesis from gram to kilogram scale.

Basic Information

Product Name	2-Amino-5-(n-Boc-Piperidin-3-Yl)Pyridine
CAS No.	1563529-74-7
Molecular Formula	C15H23N3O2
Molecular Weight	277.36 g/mol
Synonyms	2-Amino-5-(3-((tert-Butoxycarbonyl)amino)piperidin-1-yl)pyridine; tert-Butyl 3-(6-aminopyridin-3-yl)piperidine-1-carboxylate; 5-(1-(tert-Butoxycarbonyl)piperidin-3-yl)pyridin-2-amine; 2-Amino-5-(1-Boc-3-piperidyl)pyridine; 2-Amino-5-(N-Boc-piperidin-3-yl)pyridine; 1563529-74-7; 2-Pyridinamine, 5-[3-[[(1,1-dimethylethoxy)carbonyl]amino]-1-piperidinyl]-
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(n-Boc-Piperidin-3-Yl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.