Description

(1-(Fluoromethyl)Cyclopropyl)Methanamine Hcl is a specialized organic building block featuring a cyclopropane ring substituted with a fluoromethyl and an amine hydrochloride group. This compound is valued for its unique structural motif, which imparts specific steric and electronic properties, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or insecticides, where the cyclopropyl and fluorine motifs can enhance biological activity and stability.
• Chemical Biology Probe Development: Serves as a versatile scaffold for constructing molecular probes to study enzyme function or protein-ligand interactions.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers with specific thermal or surface properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	(1-(Fluoromethyl)Cyclopropyl)Methanamine Hydrochloride
CAS No.	1550947-28-8
Molecular Formula	C5H11ClFN
Molecular Weight	139.60 g/mol
Synonyms	(1-(Fluoromethyl)cyclopropyl)methanamine hydrochloride; 1-(Fluoromethyl)cyclopropanemethylamine HCl; (1-(Fluoromethyl)cyclopropyl)methylamine hydrochloride; (1-Fluoromethyl-cyclopropyl)-methylamine HCl; (Aminomethyl)(1-(fluoromethyl)cyclopropane) hydrochloride; Cyclopropanemethanamine, 1-(fluoromethyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (1-(Fluoromethyl)Cyclopropyl)Methanamine Hcl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.