Description

2-((2R,3R)-3-(tert-Butyl)-4-Methoxy-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Pyridine is a high-purity, chiral organophosphorus compound of significant interest in advanced synthetic chemistry. Its value lies in its role as a sophisticated ligand or building block for the development of novel catalysts and active pharmaceutical ingredients (APIs). This product is essential for research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create enantiomerically pure compounds. We supply this material with stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Catalyst Ligand Synthesis: Serves as a sophisticated precursor for constructing novel asymmetric catalysts used in enantioselective hydrogenation and cross-coupling reactions.
• Agrochemical Research: Used in the development of new, more effective chiral pesticides and herbicides with improved environmental profiles.
• Material Science: Potential building block for advanced functional materials, such as chiral polymers or metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable tool for chemists exploring new reaction methodologies and the properties of complex heterocyclic systems.

Basic Information

Product Name	2-((2R,3R)-3-(tert-Butyl)-4-Methoxy-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Pyridine
CAS No.	1542796-07-5
Molecular Formula	C19H24NO2P
Molecular Weight	329.37 g/mol
Synonyms	(2R,3R)-3-(tert-Butyl)-4-Methoxy-2-(pyridin-2-yl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; 2-[(2R,3R)-3-tert-Butyl-4-methoxy-2,3-dihydro-1,3-benzoxaphosphol-2-yl]pyridine; (R,R)-3-tert-Butyl-4-methoxy-2-(2-pyridyl)-2,3-dihydro-1,3-benzoxaphosphole; Chiral Dihydrobenzoxaphosphole-Pyridine Ligand Precursor; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of 2-((2R,3R)-3-(tert-Butyl)-4-Methoxy-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Pyridine adheres to strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR for structural confirmation, and purity assessment. Certificates of Analysis (COA) detailing all specifications are provided to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and opened under inert atmosphere (e.g., nitrogen or argon) for optimal long-term stability and to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.