Description

(R)-1-Phenylethanamine (1R,2R)-2-(2-Bromo-5-Methoxyphenyl)-1-(Hydroxymethyl)Cyclopropanecarboxylate is a high-purity, chiral organic compound featuring a complex molecular architecture with a cyclopropane core. This compound is of significant value as a sophisticated intermediate or building block in advanced organic synthesis, particularly for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by pharmaceutical R&D teams and custom synthesis organizations working on novel drug candidates, agrochemicals, and specialty materials where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: Key chiral building block in the research and synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) or antiviral targets.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A critical component for fine chemical manufacturers offering bespoke synthesis services to the pharmaceutical and biotechnology industries.
• Academic & Industrial Research: Utilized in chemical research for studying cyclopropane chemistry, stereoselective reactions, and structure-activity relationships (SAR).
• Material Science: Potential intermediate for creating specialty polymers or liquid crystals with specific optical properties.

Basic Information

Product Name	(R)-1-Phenylethanamine (1R,2R)-2-(2-Bromo-5-Methoxyphenyl)-1-(Hydroxymethyl)Cyclopropanecarboxylate
CAS No.	1542139-03-6
Molecular Formula	C20H22BrNO4
Molecular Weight	420.30 g/mol
Synonyms	(1R,2R)-2-(2-Bromo-5-methoxyphenyl)-1-(hydroxymethyl)cyclopropanecarboxylic acid (R)-1-phenylethanamine salt; (R)-α-Methylbenzylamine (1R,2R)-2-(2-bromo-5-methoxyphenyl)-1-(hydroxymethyl)cyclopropanecarboxylate; (R)-1-Phenylethylammonium (1R,2R)-2-(2-bromo-5-methoxyphenyl)-1-(hydroxymethyl)cyclopropanecarboxylate; (R)-PEA salt of (1R,2R)-cyclopropane carboxylic acid derivative; Bromo-methoxy cyclopropane carboxylate amine salt; Chiral cyclopropane intermediate 1542139-03-6
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and commercial projects with customized specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.