Description

1-Azaspiro[4.4]Nonane-1-Carboxylic Acid, 4-Oxo-, 1,1-Dimethylethyl Ester is a high-value, protected spirocyclic amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique spirocyclic and oxo-functionalized structure makes it an essential intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), peptidomimetics, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Peptidomimetic Synthesis: Used to introduce conformational constraints and enhance the metabolic stability of peptide-based therapeutics.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function and protein-protein interactions.
• Advanced Material Research: Explored as a monomer or additive for creating specialty polymers with unique thermal or mechanical properties.

Basic Information

Item	Details
Product Name	1-Azaspiro[4.4]Nonane-1-Carboxylic Acid, 4-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	1540034-11-4
Molecular Formula	C13H21NO3
Molecular Weight	239.31 g/mol
Synonyms	tert-Butyl 4-oxo-1-azaspiro[4.4]nonane-1-carboxylate; 1-Boc-4-oxo-1-azaspiro[4.4]nonane; 1-(tert-Butoxycarbonyl)-4-oxo-1-azaspiro[4.4]nonane; Boc-1-Azaspiro[4.4]nonan-4-one-1-carboxylate; 4-Oxo-1-azaspiro[4.4]nonane-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-oxo-1-azaspiro[4.4]nonane; 1-Azaspiro[4.4]nonan-4-one, 1-(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our production of 1-Azaspiro[4.4]Nonane-1-Carboxylic Acid, 4-Oxo-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.