Description

Spiro[2.3]Hexan-1-Ylmethanamine is a specialized spirocyclic amine building block of significant interest in advanced organic synthesis. This compound matters for its unique three-dimensional structure, which provides a rigid scaffold that can impart desirable pharmacological properties to drug candidates. Pharmaceutical and agrochemical researchers need it for the development of novel active ingredients, particularly in fragment-based drug discovery and as a key intermediate for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its spirocyclic framework for enhanced bioactivity.
• Fragment-Based Drug Discovery (FBDD): Serves as a valuable three-dimensional "fragment" in screening libraries to identify novel drug leads.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function and biological pathways.

Basic Information

Product Name	Spiro[2.3]Hexan-1-Ylmethanamine
CAS No.	1540020-17-4
Molecular Formula	C8H15N
Molecular Weight	125.21 g/mol
Synonyms	1-(Aminomethyl)spiro[2.3]hexane; Spiro[2.3]hexane-1-methanamine; 1-Spiro[2.3]hexanylmethylamine; (Spiro[2.3]hexan-1-yl)methanamine; 1-(Aminomethyl)-1-spiro[2.3]hexane; Aminomethylspiro[2.3]hexane
EINECS	Contact for details

Quality Control

Our Spiro[2.3]Hexan-1-Ylmethanamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.