Description

25B-Nbf (Hydrochloride) is a high-purity synthetic organic compound, specifically a hydrochloride salt form of a novel psychoactive substance (NPS) research chemical. This product is of significant interest for forensic, toxicological, and pharmacological research, providing a reliable reference standard for analytical method development and substance identification. It is primarily utilized by analytical laboratories, government agencies, and academic institutions engaged in controlled substance analysis, metabolism studies, and receptor activity profiling.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for qualitative and quantitative analysis in forensic and clinical toxicology.
• Forensic Science: Critical for the identification and confirmation of novel psychoactive substances (NPS) in seized materials and biological samples.
• Metabolism Studies: Used in in vitro and in vivo research to investigate metabolic pathways and identify biomarkers of consumption.
• Pharmacological Research: Serves as a tool compound for studying receptor binding affinity, functional activity, and structure-activity relationships (SAR) at serotonin and other relevant receptors.
• Method Development & Validation: Essential for developing, calibrating, and validating analytical methods using techniques like GC-MS, LC-MS/MS, and HPLC.
• Quality Control: Employed by manufacturers and testing laboratories to ensure the purity and consistency of other chemical batches or products.

Basic Information

Product Name	25B-Nbf (Hydrochloride)
CAS No.	1539266-17-5
Molecular Formula	C17H20BrNO2 • HCl
Molecular Weight	394.71 g/mol (Free base: 358.25 g/mol)
Synonyms	2-(4-Bromo-2,5-dimethoxyphenyl)-N-[(2-fluorophenyl)methyl]ethanamine Hydrochloride; 25B-NBOMe Hydrochloride (common misnomer); 2C-B-NBOMe Hydrochloride; 25B-NBF HCl; Cimbi-36; 4-Bromo-2,5-dimethoxy-N-[(2-fluorophenyl)methyl]benzeneethanamine Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 25B-Nbf (Hydrochloride) is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous identity confirmation, purity assessment, and impurity profiling to ensure they meet the exacting standards required for scientific research. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥98% by HPLC), identity confirmation (IR, NMR, MS), and residual solvent analysis is provided with each shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (1H NMR)
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.