Description

5-Bromo-4-Chloro-2-Iodo-Benzoic Acid is a highly functionalized benzoic acid derivative, serving as a critical multi-halogenated building block in advanced organic synthesis. Its value lies in providing three distinct halogen handles (Br, Cl, I) for sequential or selective cross-coupling reactions, enabling the rapid construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A versatile precursor for synthesizing complex drug molecules, especially in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where halogenated aromatic cores are key structural motifs.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials requiring halogenated aromatic units.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological systems and mechanisms.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic methodologies.

Basic Information

Product Name	5-Bromo-4-Chloro-2-Iodo-Benzoic Acid
CAS No.	1539228-96-0
Molecular Formula	C7H3BrClIO2
Molecular Weight	361.36 g/mol
Synonyms	2-Iodo-5-bromo-4-chlorobenzoic acid; 4-Chloro-5-bromo-2-iodobenzoic acid; Benzoic acid, 5-bromo-4-chloro-2-iodo-; 5-Bromo-4-chloro-2-iodobenzoic acid; 1539228-96-0
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-2-Iodo-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and stored in a dark place to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.