Description

T-Bubrettphos Palladacycle Gen. 3 is a third-generation, Buchwald-type palladium precatalyst designed for superior performance in cross-coupling reactions. This advanced catalyst offers exceptional stability and reactivity, enabling efficient and scalable synthesis of complex molecules. It is an essential tool for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries seeking robust and reliable catalytic solutions.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key C–N, C–O, and C–C bond formations for active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Facilitating the synthesis of novel herbicides, fungicides, and insecticides.
• Materials Science Research: Used in the development of organic electronic materials, polymers, and ligands.
• Academic & Process R&D: A preferred precatalyst for method development and optimization of challenging coupling reactions.
• Scale-up and Pilot Plant Operations: Provides consistent performance and handling advantages for transitioning from lab to production scale.

Basic Information

Product Name	T-Bubrettphos Palladacycle Gen. 3
CAS No.	1536473-72-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BrettPhos Palladacycle Gen. 3; t-BuBrettPhos Pd G3; Palladium t-BuBrettPhos Chloride Dimer; Chloro(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II); Third Generation BrettPhos Precatalyst; Pd-PEPPSI-IPentCl Precatalyst Analog; Buchwald Palladacycle Precatalyst
EINECS	Contact for details

Quality Control

Our T-Bubrettphos Palladacycle Gen. 3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistent catalytic performance. Certificates of Analysis (COA) detailing lot-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. The product is hygroscopic and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain optimal activity.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Pd Content	Contact for details
Solubility	Soluble in common organic solvents (THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.