Description

(S)-2-(Piperidin-2-Yl)Acetic Acid Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern pharmaceutical research and development. This compound matters because it provides a critical, enantiomerically pure scaffold for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular diseases. Pharmaceutical companies, biotechnology firms, and advanced contract research organizations (CROs) need this material for drug discovery, process development, and the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Drug Discovery & Medicinal Chemistry: Used as a versatile building block for constructing compound libraries and optimizing lead molecules in high-throughput screening campaigns.
• Asymmetric Synthesis: Serves as a precursor for chiral catalysts or ligands used in enantioselective chemical transformations.
• Peptidomimetic Research: Incorporated into peptide analogs to enhance metabolic stability and bioavailability in therapeutic peptide design.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and receptor interactions.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for commercial drug manufacturing.

Basic Information

Product Name	(S)-2-(Piperidin-2-Yl)Acetic Acid Hydrochloride
CAS No.	1536470-43-5
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	(S)-2-(2-Piperidyl)acetic acid hydrochloride; (S)-Piperidine-2-acetic acid hydrochloride; (2S)-2-(Piperidin-2-yl)acetic acid hydrochloride; L-Homopipecolic acid hydrochloride; (S)-2-Piperidineacetic acid hydrochloride; (S)-Aminomethylvaleric acid hydrochloride; 1536470-43-5
EINECS	Contact for details

Quality Control

Our (S)-2-(Piperidin-2-Yl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.