Description

5-Bromo-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine is a high-purity, advanced pharmaceutical intermediate featuring a halogenated, fused heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers targeting kinase inhibition and other therapeutic areas. The CAS number for this compound is 1534381-80-0.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve drug-like properties.
• Chemical Biology Probes: Serves as a core scaffold for developing molecular probes to study biological pathways and protein functions.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.
• Material Science: Can be utilized in the synthesis of organic electronic materials and ligands for catalysis due to its electron-rich heterocyclic system.

Basic Information

Product Name	5-Bromo-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine
CAS No.	1534381-80-0
Molecular Formula	C10H9BrN2
Molecular Weight	237.10 g/mol
Synonyms	5-Bromo-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-2-cyclopropyl-; 1534381-80-0; 5-Bromo-2-cyclopropyl-7-azaindole; 5-Bromo-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine; 2-Cyclopropyl-5-bromo-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.