Description

5-Oxa-2-Aza-Spiro[3.4]Octane Hemioxalate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for constructing novel molecular architectures, particularly in the development of protease inhibitors and other bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for lead optimization and new active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting enzymatic pathways.
• Protease Inhibitor Scaffold: Core structure in the research and development of inhibitors for various proteases (e.g., viral, serine proteases).
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies due to its constrained spirocyclic geometry.
• Chemical Biology Probes: Serves as a precursor for designing molecular probes to study biological mechanisms and protein function.
• Agrochemical Synthesis: Intermediate in the development of new active ingredients with potential herbicidal or insecticidal properties.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for exploring new chemical spaces and reaction methodologies.

Basic Information

Item	Details
Product Name	5-Oxa-2-Aza-Spiro[3.4]Octane Hemioxalate
CAS No.	1523618-29-2
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	5-Oxa-2-azaspiro[3.4]octane hemioxalate; 2-Aza-5-oxaspiro[3.4]octane hemioxalate; Spiro[3.4]octane-2-aza-5-one hemioxalate (related); Oxazaspirooctane hemioxalate; 1523618-29-2; 5-Oxa-2-azaspiro[3.4]octane, oxalic acid (1:0.5); 5-Oxa-2-azaspiro[3.4]octane compound with oxalic acid (2:1)
EINECS	Contact for details

Quality Control

Our 5-Oxa-2-Aza-Spiro[3.4]Octane Hemioxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.