Description

5-Azaspiro[3.4]Octane Oxalate is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic amine structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disorder research. Its precise molecular architecture makes it a critical component for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional degrader molecules.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with novel modes of action.
• Academic & Contract Research: Employed in university and CRO settings for exploratory synthetic chemistry and method development.

Basic Information

Product Name	5-Azaspiro[3.4]Octane Oxalate
CAS No.	1523618-05-4
Molecular Formula	C9H15NO5
Molecular Weight	217.22 g/mol
Synonyms	5-Azaspiro[3.4]octane, oxalic acid salt; 5-Azaspiro[3.4]octane oxalate salt; 1-Oxa-5-azaspiro[3.4]octane oxalate; Azaspirooctane oxalate; Spiro[3.4]octan-5-amine oxalate; 5-Aza-spiro[3.4]octane hydrogen oxalate; 1523618-05-4
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[3.4]Octane Oxalate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with ICH Q7 guidelines and can accommodate specific customer requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.