Description

1,7-Diazaspiro[3.5]Nonane-7-Carboxylic Acid tert-Butyl Ester Hemioxalate is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic diaza structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on innovative drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing processes under GMP conditions.
• Proteolysis Targeting Chimera (PROTAC) Development: Its structure makes it a potential candidate for use in linker or warhead components for targeted protein degradation therapeutics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1,7-Diazaspiro[3.5]Nonane-7-Carboxylic Acid tert-Butyl Ester Hemioxalate
CAS No.	1523617-82-4
Molecular Formula	C13H22N2O5
Molecular Weight	286.33 g/mol
Synonyms	tert-Butyl 1,7-diazaspiro[3.5]nonane-7-carboxylate hemioxalate; 1,7-Diazaspiro[3.5]nonane-7-carboxylic acid, 1,1-dimethylethyl ester, (T-4)-; 7-(tert-Butoxycarbonyl)-1,7-diazaspiro[3.5]nonane hemioxalate; BOC-1,7-Diazaspiro[3.5]nonane hemioxalate; 1,7-Diazaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester oxalate (1:0.5); Spirocyclic diaza building block
EINECS	Contact for details

Quality Control

Our 1,7-Diazaspiro[3.5]Nonane-7-Carboxylic Acid tert-Butyl Ester Hemioxalate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be developed to meet specific customer requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.